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Symbol
Name
ID
Fen1
flap structure specific endonuclease 1
MGI:102779
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
thymus atrophy
enlarged spleen
increased plasma cell number
abnormal spleen B cell follicle morphology
increased spleen B cell follicle number
increased spleen B cell follicle size
abnormal spleen marginal zone morphology
pale spleen
lymphoid hyperplasia
increased susceptibility to autoimmune disorder
increased anti-nuclear antigen antibody level
increased anti-double stranded DNA antibody level
chronic inflammation
glomerulonephritis
lung inflammation
interstitial pneumonia
Availability Mouse Genotype
Fen1tm1Bhsh/Fen1tm1Bhsh
Fen1tm2Klng/Fen1tm2Klng *
Fen1tm3.1Bhsh/Fen1tm3.1Bhsh
Fen1tm1Rak/Fen1+
Fen1tm3.1Bhsh/Fen1+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory